PATHWAY ANALYSIS FOR DRUG DISCOVERY Computational Infrastructure and Applications

Pathway analysis is a rapidly developing discipline that combines software tools, database models, and computational algorithms — all of which help molecular biologists to convert molecular interaction data into a set of computational models. The models are developed for better prediction of cell behavior in response to a drug, nutrients, or other outside stimuli. The development of pathway analysis was triggered by the expansion of high - throughput methods and the completion of human genome sequencing project. Because of these technological advances, the emphasis of molecular biology has shifted from reductionism to system integration.